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Warfarin is the most common medication used in the United States for anticoagulant therapy. It is sold under the brand names Coumadin and Jantoven. Certain proteins need to be circulating in the blood in order for it to be able to clot. The proteins are formed in the liver and the body needs vitamin K to be able to produce them. Warfarin is a vitamin K antagonist. Anticoagulant medications are commonly called "blood thinners", but they do not actually thin the blood; they interfere with the ability to make a clot. Warfarin accomplishes this by interfering with vitamin K. It was developed as a drug in the 1950s from spoiled sweet clover. Scientists noticed that if cattle ate too much of it, they developed a tendency to bleed.
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